Aurora
Dehydrated Amniotic Membrane Allograft
Patent-Pending Central Aperture Design · FORMULA/5™ Processing · E-Beam Sterilized
Aurora delivers the full regenerative matrix of dehydrated amniotic membrane with a patent-pending 5 mm central aperture that preserves the visual axis throughout the dissolution cycle — enabling functional central vision from placement to resolution.
Three innovations that set Aurora apart.
Aurora was engineered from the ground up to address the clinical limitations of first-generation amniotic membrane products — not to replicate them.
Patent-Pending Central Aperture
The 5 mm central aperture is Aurora's defining innovation. Solid-disc designs block the visual axis entirely — Aurora preserves it. Patients retain functional central vision from placement through dissolution, improving compliance and enabling bilateral same-session treatment.
No central visual blackout. No compliance barrier.
FORMULA/5™ Processing
Conventional processing — freeze-drying, solvent extraction, chemical cross-linking — denatures the growth factors that drive healing. FORMULA/5™ minimal-manipulation air-drying preserves the full bioactive complement: EGF, bFGF, TGF-β, PDGF, HGF, and the complete anti-inflammatory cytokine profile.
Full bioactivity. No chemical compromise.
Room-Temperature Stability
E-beam sterilization eliminates pathogens without chemical cross-linking. Room-temperature storage means no cold chain management, no freezer logistics, and no risk of inadvertent thaw-refreeze cycles that compromise tissue quality — from your rep's bag to the exam chair.
No cold chain. No freezer. No excuses.
Regenerative Membrane Therapy — Reimagined for the Visual Axis.
Aurora is a dehydrated amniotic membrane (dAM) allograft processed under Ophthalogix's proprietary FORMULA/5™ protocol — a minimal-manipulation, air-drying method that preserves the full complement of growth factors, cytokines, and extracellular matrix proteins responsible for the regenerative cascade.
The patent-pending 5 mm central aperture distinguishes Aurora from conventional solid-disc designs. By leaving the visual axis unobstructed, Aurora eliminates the central visual blackout associated with full-coverage membranes — a clinically meaningful advantage for patient comfort, compliance, and bilateral treatment protocols.
Product Specifications
Broad ICD-10 Coverage Across the Ocular Surface Spectrum.
Aurora is indicated for a wide range of ocular surface conditions where regenerative membrane therapy is clinically appropriate.
Corneal Conditions
Ocular Surface & Conjunctival
ICD-10 codes are provided for educational reference. Coding must reflect the actual diagnosis and clinical documentation. Consult current payer guidelines and your compliance team before submission.
Three Biological Pillars. One Regenerative Cascade.
Aurora's regenerative activity is driven by the preserved biological matrix of human amniotic membrane — a tissue uniquely suited to ocular surface restoration.
Growth Factor Delivery
FORMULA/5™ processing preserves the full bioactive complement: EGF, bFGF, TGF-β, PDGF, HGF, and VEGF. These mediators drive epithelial proliferation, stromal remodeling, and neovascular regulation at the wound site.
Extracellular Matrix Scaffold
The intact basement membrane complex — collagen IV, laminin, fibronectin, and proteoglycans — provides a structural scaffold that guides epithelial cell migration and supports organized tissue regeneration rather than fibrotic scar formation.
Anti-Inflammatory Modulation
Amniotic membrane is inherently immunoprivileged. Aurora delivers IL-1RA, IL-10, and TSG-6 — cytokines that suppress the pro-inflammatory cascade, reduce MMP activity, and create a permissive environment for regeneration rather than chronic inflammation.
Designed Around the Clinician. Optimized for the Patient.
Every design decision in Aurora addresses a real clinical friction point — from patient compliance to procedural efficiency to billing confidence.
Visual Axis Preservation
The 5 mm central aperture eliminates the central visual blackout inherent to solid-disc designs. Patients retain functional central vision from placement through dissolution — improving compliance and enabling bilateral same-session treatment.
Full Bioactive Matrix
FORMULA/5™ processing preserves the complete growth factor and cytokine profile. No solvents, no chemical cross-linkers, no freeze-drying cycles that denature the proteins responsible for the regenerative cascade.
Office-Based Efficiency
Aurora is designed for in-office application with a bandage contact lens — no surgical suite, no general anesthesia, no OR scheduling friction. Integrate into existing anterior segment workflows with minimal disruption.
Anti-Fibrotic Remodeling
The preserved anti-inflammatory cytokine profile — IL-1RA, IL-10, TSG-6 — suppresses MMP activity and modulates the fibrotic cascade, supporting clear, organized epithelial regeneration rather than scar tissue formation.
Broad Indication Coverage
Twenty-plus ICD-10 covered indications spanning corneal ulcers, keratitis, pterygium, dry eye disease, chemical burns, and post-surgical ocular surface compromise — one product across the full spectrum of anterior segment practice.
Regulatory & Quality Assurance
Processed under FDA 21 CFR Part 1271 HCT/P regulations at an AATB-accredited tissue bank. E-beam sterilization without chemical cross-linking. Room-temperature storage — no cold chain management required.
Not all amniotic membrane is the same.
The regenerative activity of amniotic membrane is directly dependent on processing methodology. Conventional approaches — aggressive freeze-drying, solvent extraction, chemical cross-linking — denature the growth factors and cytokines that drive the healing cascade. FORMULA/5™ was developed specifically to avoid these compromises.
Minimal-manipulation air-drying preserves the full biological matrix from donor to patient. E-beam sterilization eliminates pathogens without the chemical cross-linking that compromises bioactivity. The result is a membrane that retains the regenerative potential of fresh amniotic tissue in a room-temperature, shelf-stable format.
A Reimbursable Procedure with Established Coding Pathways.
Amniotic membrane transplantation is a well-established, reimbursable procedure under Medicare and most commercial payers. Ophthalogix provides dedicated practice support to help your team navigate coding, documentation, and billing workflows.
CPT Coding Reference
Placement of amniotic membrane on the ocular surface; without sutures
Primary code for office-based Aurora application
Placement of amniotic membrane on the ocular surface; single layer, sutured
Surgical suite application with suture fixation
Ocular surface reconstruction; amniotic membrane transplantation, multiple layers
Multi-layer reconstruction for complex surface disease
Amniotic membrane per square centimeter (HCPCS tissue code)
Facility/ASC billing — confirm with payer
CPT code selection must reflect the actual procedure performed. Reimbursement rates are approximate Medicare averages and vary by MAC jurisdiction, facility type, and payer.
Reimbursement Support
Practice Integration
Available Now. Direct and Through Authorized Distributors.
Aurora is available for direct order through Ophthalogix and through authorized ophthalmic distributors. Contact your regional representative or our clinical support team to establish an account.
Contact your Ophthalogix representative for current pricing, volume discounts, and consignment program availability.
More Than a Graft. A Clinical Partnership.
Ophthalogix provides the clinical education, reimbursement support, and direct physician access that transforms a product relationship into a practice-building partnership.
Call Us
(888) 772-6646
Mon–Fri, 8 AM–6 PM CT
info@ophthalogix.com
Clinical & ordering inquiries
Headquarters
4766 Research Drive
San Antonio, TX 78240
Aurora is a human tissue product regulated under FDA 21 CFR Part 1271. This document is intended for licensed healthcare professionals and is provided for educational and informational purposes only. Product information is subject to applicable labeling, regulation, and clinical judgment. Refer to the current Instructions for Use for complete product-specific information, contraindications, warnings, and precautions. CPT codes and reimbursement rates are provided for reference only and do not constitute coding or billing advice. Consult current payer guidelines and your compliance team before submission.
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